Description
Product Characteristics: Pex1, peroxisomal biogenesis factor 1, ZWS1, peroxin1, peroxisome biogenesis disorder protein 1, 5430414H02Rik, E330005K07Rik, MGC102188
Target Information: This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. [provided by RefSeq, Jul 2008]